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Piperine enhances absorption of topical ingredients

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by Jacob » December 16, 2007 at 5:13 pm #68786

Cosmoperine®
A cosmeceutical that augments the efficacy of administered topical ingredients is Cosmoperine®, Sabinsa’s natural, skin permeation enhancer prepared from piperine, the active principle of black pepper (Piper nigrum) and long pepper (Piper longum). Cosmoperine® can be added to finished cosmetic products (e.g. lotions, creams, balms, etc.) to enhance the absorption of the active compounds and nutrients in the formulations.

Maybe plain piperine wouldn’t work..

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by Jacob » December 16, 2007 at 5:25 pm #68791

I see they have a website on just this:

Efficacy studies, etc.

Interesting “Absorption and Bioavailability” distinction..discussion:

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by balance » December 16, 2007 at 6:58 pm #68809

Damn, that’d be some nice stuff for all us making homemade topicals seeing as it likely won’t mess with TGF-beta etc.

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by Jacob » December 16, 2007 at 7:04 pm #68811

I noticed there are some companies using it in their patches: “The Development Team has maximized the efficacy of ForsLean and the overall effectiveness of the Patch by increasing the ingredient transdermal uptake through the addition of Cosmoperine®, the active ingredient of black pepper and long pepper. Cosmoperine allows the Patch to offer increased delivery and patch performance without compromising factors like gentleness or skin irritation. Homeopathically potentiated thyreodinum extract also helps maintain the careful balance Patch is known for.”

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by Leva » December 16, 2007 at 7:07 pm #68812

Piperine is also supposed to be a potent 5alpha-reductase inhibitor. Would be cool if it helped absorption. I do not think I ever heard of any one thing working both ways like that.

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by BobTheBuilder » December 17, 2007 at 2:17 am #68859

Supplier?

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by bcapop » December 17, 2007 at 10:11 am #68883

Good find Jacob. Maybe this will help the RU absorb.

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by Jacob » December 17, 2007 at 10:15 pm #68975

Best to email the company(they have a USA contact as well)..otherwise I’ve seen suppliers in Korea.

I noticed a bunch of cosmetic products containing it. Some that also use liposomes. Here’s one with cu peptides and all kinds of other goodies:
Cucumber Extract in Deionized Water, 10% Vitamin C Esters(8.9% ascorbyl palmitate, 1% ascorbyl tetraispalmitate and .1% dl-a-tocopheryl 2 L ascorbyl phosphate), Lanol(vegetable origin), Montanov68(vegetable origin), Liposome Carrier System, Sodium Hyaluronate(vegetable origin), Red Algae Extract, Borage Oil, 1.5% DMAE, 1% Alpha Lipoic Acid, Sepigel, Sodium PCA, Copper Peptides, Amino Acid Complex, Germall, Fennel Oil, 0.5%Tocorienols(High Potency Vitamin E), 0.25% Retinol, 0.1% Cosmoperine, 0.025% Micronized Natural Progesterone, 0.005% Micronized Natural Estriol.

A growth/regrowth patent that talks about it:

Vit K cream with it:

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by Jacob » December 17, 2007 at 10:41 pm #68983

Here’s one in Canada:

See

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by Jacob » May 28, 2009 at 9:15 pm #122288

Old post..but I wonder if this would work in a shampoo. Still looks good for topicals as well.

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