Off-Label Treatments

Turosteride

Hair Loss Treatment Type: Anti-androgen Availability: Prescription Notes: This seems to be a promising new anti-androgen. Claimed Results: None. Observed Results: Unknown. Clinical Results: Anti-androgenic effects. Testing: Some. Safety/Side Effects: Unknown. Gender: Either. Typical Cost: Unknown.

Tempo (Tempol)

Hair Loss Treatment Type: Nitroxide used as Superoxide Dismutase Availability: Prescription Notes: Tempo/Tempol is a member of the super oxide dismutase class drugs. Currently it is only approved by the FDA for the treatment of hair loss in cancer patients. Reason for rating: Not available to most people and probably expensive. Studies involve cancer patients,   …Continue Reading

Tagamet (Cimetidine)

Hair Loss Treatment Type: Antacid, Anti-androgen Availability: Over the counter. Notes: Tagamet is an antacid, anti-heartburn drug that is available over the counter. In large multiple doses daily, it can have anti-androgen effects. These effects are fairly weak though and you have to take a fairly large amount of the drug to get them, which   …Continue Reading

Tacrolimus (Fujimycin, FK506)

Hair Loss Treatment Type: Immunosuppressive Availability: Prescription Notes: FK506 is an immunosuppressant, like cyclosporin, primarily used to prevent organ rejection. Like Cyclosporin, it also has hair growth effects; however, unlike cyclosporin, it is more effective topically for hair growth than orally, making it a better choice than cyclosporin. Unfortunately, like cyclosporin, it also has the   …Continue Reading

Pinacidil

Hair Loss Treatment Type: Hypertensive / Potassium Channel Opener Availability: Prescription Notes: Pinacidil (and its analogue PC-1075) are hypertensive similar to minoxidil in many ways. Pinacidil is a true Potassium (K+) channel opener and shown to grow hair when applied topically. Claimed Results: None. Observed Results: Unknown. Clinical Results: Moderate hair growth. Testing: Some testing.   …Continue Reading

Lupron (Leuprolide Acetate)

Hair Loss Treatment Type: GNrH Agonist Claimed Results: None. Observed Results: Unknown. Clinical Results: Helps with hirsutism. Testing: Some testing. Safety/Side Effects: Unknown. Gender: Primarily female. Typical Cost: Unknown.

Inocoterone

Hair Loss Treatment Type: Antiandrogen Notes: This is a true antiandrogen that binds to the receptor and prevents hormones from binding. From the study, it seems to have modest effects. Claimed Results: None. Observed Results: Unknown. Clinical Results: Unknown. Testing: Some testing. Safety/Side Effects: Unknown. Gender: Either. Typical Cost: Unknown.

Flutamide (Euflex, Eulexin)

Hair Loss Treatment Type: Antiandrogen Availability: Prescription Flutamide is one of the most powerful pure antiandrogens that blocks the androgen receptor so that androgens will have no effect on the body. Unfortunately, it is systemic so it is not recommended for men. Some doctors use it in very small doses topically in men in combination   …Continue Reading

Estradiols (Estrogens)

Hair Loss Treatment Type: Estrogens Availability: Prescription Notes: Estrogens appear to somehow compete with androgens for effect on the body. Raising the ratio of female to male hormones often helps in hair loss. This is one of the most common treatments for female alopecia, but they are not very male-friendly due to side effects. Claimed   …Continue Reading

Dilantin (Phenytoin)

Hair Loss Treatment Type: Anticonvulsant Availability: Prescription, online retailers. Notes: This drug has a known side effect of stimulating hair growth and enhancing wound healing. It is primarily used orally in the treatment of epileptic seizures. It is also one of the ‘smart drugs’. Claimed Results: None. Observed Results: Unknown. Clinical Results: Known side effect   …Continue Reading

Diazoxide

Hair Loss Treatment Type: Hypertensive / Potassium Channel Opener Availability: Prescription. Notes: Diazoxide is one of several hypertensive (blood pressure lowering) agents that has a positive effect on hairless likely due to its ability to open potassium channels). Unfortunately, it’s expensive and difficult to get in topical form. Other treatments are likely more effective as   …Continue Reading

Diane-35

Hair Loss Treatment Type: Anti-androgen / Estrogen Availability: Prescription. Notes: This is a low-dose contraceptive that came out in the late 70s / early 80s as an alternative to normal oral contraceptives. It has been shown to have a good effect against hirsutism and even hair loss. Claimed Results: None. Observed Results: Unknown. Clinical Results:   …Continue Reading

Cytadren (Aminoglutethimide)

Hair Loss Treatment Type: Adrenal Cortex Hormone Suppressant / Antiestrogen / Aromatase inhibitor / Anticortisol Availability: Prescription. Notes: Cytadren is a drug used to treat overactive adrenal cortexes. The adrenals produce female estrogens/estradiols, cortisol (used in your body’s reaction to stress) and some precursor hormones (DHEA). It is often used by weight lifters to suppress   …Continue Reading

Cyclosporin

Hair Loss Treatment Type: Immunosuppressive Availability: Prescription. Notes: Cyclosporin is a drug typically used in organ transplants to prevent the body rejecting the organ by suppressing the immune system. It is also used topically in the treatment of some severe skin conditions. Cyclosporin has been shown to be very effective orally and only minimally effective   …Continue Reading

Cromakalim (BRL 34915)

Hair Loss Treatment Type: Potassium (K+) channel opener Availability: Prescription. Notes: This is a potassium channel opener used in the treatment of heart conditions primarily. Tests show that it works for hair growth in the same way as minoxidil. Claimed Results: None. Observed Results: Unknown. Clinical Results: Studies show Cromakalim works similarly to minoxidil. Larger   …Continue Reading

Casodex (Bicalutamid, ICI 176,334)

Hair Loss Treatment Type: Anti-androgen Availability: Prescription. Notes: Casodex is a new derivitive of Flutamide, one of the most powerful pure ant-iandrogens that blocks the androgen receptors, so that androgens will have no effect on the body. Unlike Flutamide, which has several side-effects and semi-toxic effects, Casodex is much more side effect free. Claimed Results:   …Continue Reading

Buserelin (HOE 766)

Hair Loss Treatment Type: Gonadatropin Releasing Hormone (GNrH) Agonist Availability: Prescription. Notes: This treatment has been tested and shown to be effective for hirsutism in women. Generally, what works for hirsutism will work for hair loss. Claimed Results: None. Observed Results: Unknown. Clinical Results: Improvement on hirsutism in women. Testing: Well tested. Safety/Side Effects: Reduction   …Continue Reading

Azelex (Skinoren, Azeleic Acid)

Hair Loss Treatment Type: Anti-androgen / Skin Treatment Availability: Prescription. Notes: This is a relatively new cream available for skin care by prescription. The following study indicates it may be useful as a topical anti-androgen. Claimed Results: None. Observed Results: Unknown. Clinical Results: Some clinical tests for anti-androgen properties. Testing: Some (FDA approved). Safety/Side Effects:   …Continue Reading

Androcur (Cyproterone Acetate, CPA)

Hair Loss Treatment Type: Anti-androgen / Contraceptive Availability: Prescription. Notes: One of the first anti-androgens used for hair loss treatment. Unfortunately, it has several side effects, especially in men, but it is still used in women, especially in the UK. Claimed Results: Minimal to moderate hair growth. Observed Results: Minimal to moderate hair growth. Clinical   …Continue Reading

Aldactone (Spironolactone)

Hair Loss Treatment Type: Anti-androgen Availability: Prescription. Notes: Spironolactone is one of the most powerful anti-androgens available. It is also absorbed locally when applied topically, so it is good for hair loss treatment since it is not absorbed throughout your body. Since it is so powerful, it is not used orally due to side effects   …Continue Reading