Cyproterone thiopivolate (Procter & Gamble)

United States Patent     5,439,901

Schwen, et. al.     Aug. 8, 1995

 

Inventors:

Schwen; Richard J. (Cincinnati, OH); Sine; Mark R. (Morrow, OH); Warren; Raphael (Amberly Village, OH).

 

Asignee:

The Procter & Gamble Company (Cincinnati, OH).

 

Appl. No:

096,081

 

Filed:

Jul. 23, 1993

Intl. Cl.: A61K 31/56; C07J 7/00

U.S. Cl.: 514/178; 552/511

Field of Search: 552/585, 511; 514/181, 178; 424/449

 

Abstract:

The present invention relates to the compound cyproterone thiopivalate (CTP) and compositions comprising CTP. The present invention further relates to methods of treating acne and/or sebaceous gland activity comprising topical application of CTP. The present invention additionally relates to methods of regulating hair growth comprising application of compositions comprising CTP.

5 Claims, No Drawings

References Cited:

U.S. Patent Documents

3,234,093     Feb, 1966     Wierchert et al.     167/74

4,014,909     Mar, 1977     Torossian et al.     260/397

4,098,803     Jul, 1978    Torossian et al.     260/397.45

4,098,804     July, 1978     Torossian et al.     260/397.45

4,177,268     Dec, 1979     Torossian et al.     424/243

4,269,778     May, 1981     Torossian et al.     260/397.45

4,361,559     Nov, 1982     Varma     424/243

4,861,765     Aug, 1989     Mituskuchi et al.     514/181

4,877,781     Oct, 1989     LaHaye et al.     514/179

5,021,408     Jun, 1991     Aubard et el.     514/179

Foreign Patent Documents

0163490     Dec, 1985     EP

4006165A1     Feb, 1990     DE

86/01402     Mar, 1986     WO

93/13122     May, 1992     WO

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Primary Examiner: Richter; Johann
Assistant Examiner: Cook; Rebecca
Attorney, Agent or Firm: Corstanje; Brahm J., Suter; David L., Rasser; Jacobus C.