Hairloss Study Abstract: Pharmacological action of 101-B hair regeneration extract on skin and hair in experimental animals

Hairloss Study Abstract: Pharmacological action of 101-B hair regeneration extract on skin and hair in experimental animals

Title

[Pharmacological action of 101-B hair regeneration extract on skin and hair in experimental animals]

Author

Qian BC; Chen J; Xu HJ

Address

Inst. of Materia Medica, Zhejiang Academy of Medical Sciences, Hangzhou.

Source

Chung Kuo Chung Hsi I Chieh Ho Tsa Chih, 1994 Apr, 14:4, 227-9, 198

Abstract

Pharmacological action of 101-B hair regeneration extract (101-B) on skin and hair was studied in experimental animals. The results were as follows: (1) In normal rats, guinea pigs and rabbits the weight of regrown hairs in shaved area in 101-B group was significantly heavier than that in alcohol group. (2) Hairloss induced by oral administration of thallium carbonate 2 mg/kg every other day for 10 times was obviously prevented by topical treatment of 101-B. (3) Itching threshold to histamine or papain in guinea pig was elevated after using of 101-B topically. (4) The diameter of skin ulcer caused by intradermal injection of adriamycin in rats was diminished in 101-B group. (5) Observation in skin microcirculation in mice indicated that both normal skin microcirculation and disturbed microcirculation induced by endotoxin were improved with administration of 101-B. Above experimental results provided preliminary evidence for clinical use of 101-B.

Language of Publication

LA=CHI

Unique Identifier

95037523