Dyphylline for hair growth (Procter & Gamble)


United States Patent   H1,480

Luo    Sept. 5, 1995


Luo; Xiaochun (West Chester, OH).


The Procter & Gamble Company (Cincinnati, OH).

Appl. No:



Dec. 9, 1993


The subject invention relates to methods for promoting hair growth in mammals comprising topical application of dyphylline or a pharmaceutically-acceptable salt thereof. The subject invention further involves topical compositions comprising dyphylline.

17 Claims, No Drawings


References Cited:

U.S. Patent Documents

4,341,783     Jul, 1982     Scheindlin     424/253

Foreign Patent Documents

356271     Jul, 1989     EP

3913245     Nov, 1989     DE

62-045527     Feb, 1987     JP

Other References

Stuttgen, C., and D. Neumann, “Caffein and Skin”, Aztliche Kosmetologie vol. 19, pp. 163-187 (1980).

Seiler, W. G., “Possibilities of Preserving Hair Growth and of Controlling Dandruff and Seborrhoea in the Region of the Capillitium”, Akt. Derm. vol. 7, pp. 51-59 (1981).

Seiler, W. G., E. Bohnert, E. G. Jung, and U. Feldmann. “Local Therapy in Androgenically Caused Hairloss”, Artzliche Kosmetologie vol. 14, pp. 209-220 (1984).

Imokawa, G., Y. Yada, and Y. Hori., “Induction of Melanization Within Hair Bulb Melanocytes in Chinchilla Mutant by Melanogenic Stimulants”, Society for Investigative Dermatology, Inc., vol. 91(2), pp. 106-113 (1988).
Primary Examiner: Walsh; Donald P.
Assistant Examiner: Chi; Anthony R.