United States Patent 5,086,040
Marty Oct. 13, 1987
Marty; Jean-Pierre (Montesson, FR).
Roussel Uclaf (Paris, FR).
Apr. 23, 1985
Foreign Application Priority Data:
Apr. 26, 1984 [FR] 89-065
Intl. Cl.: A61K 7/42, A61K 9/08
Current U.S. Cl.: 424/59; 514/844; 514/859; 514/861; 514/885; 514/886; 514/887
Field of Search: 435/68, 638; 514/886, 848; 424/59
Improved cosmetic compositions for skin care containing an amount sufficient for skin care of glycoprotein extracts of lysed microbial bodies of Hafnia species or strains prepared by (a) cultivating a microbial Hafnia strain until complete development of microbial bodies, (b) subjecting the microbial bodies to lysis, (c) treating the lysate with at least one solvent for delipidation and depigmentation of the lysate, (d) dissolving the resulting product, (e) subjecting the solution to centrifugation and (f) optionally subjecting the resulting product to ultrafiltration and a method of improving a person’s skin.
10 Claims, 1 Drawing Figures
U.S. Patent Documents
4,154,821 May, 1979 Drouet et al. 541/8
4,346,109 Aug, 1982 Yamatsu et al. 541/886
Primary Examiner: Ore; Dale R.
Attorney, Agent or Firm: Bierman and Muserlian