Patent:
United States Patent 5,470,861
Harmon Nov. 28, 1995
Method of promoting hair growth.
Inventors:
Harmon; Charles S. (Bloomfield, NJ).
Assignee:
Hoffmann-La Roche Inc. (Nutley, NJ).
Appl No:
286,152
Filed:
Aug. 4, 1994
Abstract:
The use of the compound 2-(6-cyano-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine-1-oxide represented by the formula ##STR1## as well as pharmaceutically acceptable salts, as topical agents to promote hair growth is disclosed.
19 Claims, No Drawings
References Cited:
U.S. Patent Documents
4,971,982 Nov, 1990 Altwood et al. 514/337
5,028,711 Jul, 1991 Stenzel et al. 546/196
Foreign Patent Documents
9056007 Dec, 1990 AU
9058725 Jan, 1991 AU
9059751 Jan, 1991 AU
9060134 Feb, 1991 AU
9065644 May, 1991 AU
0350805 Jul, 1989 EP
0400430 May, 1990 EP
0406656A1 Jun, 1990 EP
0410208A1 Jul, 1990 EP
0427606A1 Nov, 1990 EP
3926001A1 May, 1989 DE
2204868 May, 1988 GB
WO86/00616 Jan, 1986 WO
88/00822 Feb 1988 WO
WO92/14439 Mar, 1992 WO
Other References
Uno, et al. Cyclic Dynamics of Hair Follicles and Effect of Minoxidil on the Bald Scalps of Stumptailed Macaques, The American Journal of Dermatology 7(3):283-297 (1985).
Uno, et al. Stumptailed Macaques as a Model of Male Pattern Baldness Models Dermatol. vol. 3 pp. 159-169 (1987).
Uno, H., The Stumptailed Macaque as a Model for Baldness: Effects of Minoxidil, International Journal of Cosmetic Science 8, 63-71 (1986).
Abstract (Corresponding to WO 9214439) 1992.
Primary Examiner: Henley, III; Raymond
Assistant Examiner: Spivack; Phyllis G.
Attorney, Agent or Firm: Gould; George M., Johnston; George W., Coletti; Ellen Ciambrone
