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Sulfasalazine for Alopecia

Hair Loss Study Abstract

Sulfasalazine is used as a therapy for various autoimmune conditions, including psoriasis; its effectiveness is presumed to be the result of its immunomodulatory effects. We have treated patients with severe alopecia areata with sulfasalazine as part of our dermatology practice and have noticed cosmetically acceptable regrowth in 23% of patients in whom a response could be determined. In view of its good safety profile, sulfasalazine may be considered for systemic treatment of severe alopecia areata.

Sulfasalazine, also known as Azulfidine, is a medication used to treat several autoimmune disorders. Recently, doctors studied it’s use in treating Alopecia Areata. In their study, 23% of patients taking the drug regrew their hair.

“When it works, it works great,” said study author John J. Voorhees, MD, of the University of Michigan.



Ellis CN; Brown MF; Voorhees JJ



Department of Dermatology, 1910 A. Alfred Taubman Center, University of Michigan Medical School, Ann Arbor, MI 48109-0314, USA



J Am Acad Dermatol 2002 Apr;46(4):541-4





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