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Treatment of Androgenic Alopecia with topical Minoxidil


Treatment of Androgenic Alopecia with topical Minoxidil



Brenner S, Tamir A



Dermatology Dept., Sourasky Medical Center, Tel Aviv.



Harefuah, 121: 9, 1991 Nov 1, 297-302


Hair Loss Study Abstract

Minoxidil, a vasodilator, was first marketed in 1979 as an oral antihypertensive. Since hypertrichosis occurred as an adverse effect in most patients treated, a 2% topical solution was developed for use in men with androgenic alopecia. It was approved by the American Food and Drug Administration and by the Israel Ministry of Health. A follow-up of 30 cases treated with the preparation is presented. Efficacy of treatment was assessed by hair counts in a marked area on the balding scalp, as well as by subjective evaluations of patients and physicians. The treatment was beneficial in 63%: balding was slowed in most, while in a minority hair density actually increased. However, in only 6.6% was dramatic cosmetic improvement achieved.


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